Peptides
LL-37 5mg
LL-37 is the only human cathelicidin-derived antimicrobial peptide, a 37-residue amphipathic helix released by proteolysis of hCAP18. It is studied for direct membrane-disrupting antimicrobial activity and for immunomodulatory and wound-repair signalling.
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- Same-day dispatch before 2 PM PT from British Columbia, Canada
- Free shipping over CA$200
- Batch-specific COA with every lot
- Priced in Canadian dollars
Specification
- Catalogue number
- OP-047
- Purity specification
- >99%
- Fill
- 5mg
- CAS number
- 154947-66-7
- Molecular formula
- C₂₀₅H₃₄₀N₆₀O₅₃
- Molecular weight
- 4,493.3 g/mol
- Form
- Lyophilized powder
- Solubility
- Soluble in bacteriostatic water
- Shelf Life
- 24 months from date of manufacture
About LL-37 5mg
LL-37 works through charge and shape rather than through a receptor: its cationic amphipathic helix inserts into anionic bacterial membranes and disrupts them, a mechanism that makes resistance development slow compared with conventional antibiotics. Alongside that direct activity it acts as a signalling molecule, driving chemotaxis, angiogenesis and re-epithelialisation, and it is this dual role that makes it interesting in wound-healing models. It is also implicated in the pathology of psoriasis and rosacea, so the literature cuts both ways. This 5mg vial is sized for the low working concentrations typical of antimicrobial assays.
Storage and reconstitution
Store lyophilized peptide at -20°C in a dry, dark environment. Reconstitute in bacteriostatic water. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles. Lyophilized powder is stable at room temperature for shipping and short-term storage.
Shipping within Canada
Orders placed before 2:00 PM Pacific on a business day are packed and dispatched the same day. Orders placed after that cut-off, or on a weekend or statutory holiday, are dispatched on the next business day. Parcels leave British Columbia, Canada and travel entirely within the country, so nothing on this order crosses a border, clears customs or is held by CBSA. Orders over CA$200 ship free; see the shipping page for transit times by province.
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