Melanotan Peptides
PT-141 10mg
PT-141 (bremelanotide) is a cyclic heptapeptide melanocortin agonist active principally at MC3 and MC4 receptors. It is a metabolite of Melanotan II and acts centrally rather than on the vascular periphery.
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- Same-day dispatch before 2 PM PT from British Columbia, Canada
- Free shipping over CA$200
- Batch-specific COA with every lot
- Priced in Canadian dollars
Specification
- Catalogue number
- OP-050
- Purity specification
- >99%
- Fill
- 10mg
- CAS number
- 189691-06-3
- Molecular formula
- C₅₀H₆₈N₁₄O₁₀
- Molecular weight
- 1,025.2 g/mol
- Form
- Lyophilized powder
- Solubility
- Soluble in bacteriostatic water
- Shelf Life
- 24 months from date of manufacture
About PT-141 10mg
PT-141 is what Melanotan II becomes after loss of the C-terminal amide, and that single change shifts its selectivity away from MC1R pigmentation activity toward MC3R and MC4R. Because MC4R signalling in the hypothalamus is the pathway involved, its mechanism is central rather than peripheral, which distinguishes it categorically from PDE5 inhibitors. It reached regulatory approval as Vyleesi, giving it a far more complete safety and pharmacokinetic dataset than most compounds in this catalogue. Nausea through the same central pathway is the dose-limiting effect reported across that dataset.
Storage and reconstitution
Store lyophilized peptide at -20°C in a dry, dark environment. Reconstitute in bacteriostatic water. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles. Lyophilized powder is stable at room temperature for shipping and short-term storage.
Shipping within Canada
Orders placed before 2:00 PM Pacific on a business day are packed and dispatched the same day. Orders placed after that cut-off, or on a weekend or statutory holiday, are dispatched on the next business day. Parcels leave British Columbia, Canada and travel entirely within the country, so nothing on this order crosses a border, clears customs or is held by CBSA. Orders over CA$200 ship free; see the shipping page for transit times by province.
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